Science Simplified
Science Simplified
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Відео

Why High-Protein Diets Might Be The Most Common Myth in Health (Read Summary In Description)
Переглядів 3932 години тому
Skip to 9:51 for the “muscle mass/protein” part of the video. The totality of longevity research strongly suggests HIGH mTOR activity accelerates the onset of aging, cancer, and virtually every age-related chronic diseases. However, some argue that 1) exercise activates mTOR 2) exercise is clearly good for you 3) therefore, mTOR cannot be relevant for human disease. I strongly disagree with thi...
A Common Root Cause Of Chronic Diseases? (Why Many Longevity Meds Treat Diabetes) READ SUMMARY BELOW
Переглядів 8935 місяців тому
We store calories from our diet in adipocytes. However, excessive calorie intake eventually overwhelms our adipocytes capacity to store energy, resulting in excess energy from our diet being stored in other tissues, generally referred to as ectopic fat. One of the tissues that accumulate ectopic fat is Skeletal Muscle, which store the excess energy from our diet in the form of IntraMyoCellular ...
Does Chronic Inhibition of Apoptosis Enable Oncogenesis? (Summary in Description)
Переглядів 2 тис.2 роки тому
Elephants have 4 quadrillion cells, meaning 4 quadrillion opportunities to develop just ONE cancerous cell. Despite this, they have significantly lower cancer incidence than humans. They also have x20 more copies of p53, the most commonly mutated gene found in human cancer. SUMMARY OF THEORY -DNA damage provides signals that should initiate apoptosis in precancerous cells. However, chronic expo...
The Biology of Aging & Interventions That Extend Animal Longevity (Summary in Description)
Переглядів 1,7 тис.2 роки тому
$1,000,000 cash prize was offered to the research lab that could create the longest lived mice. No rules or limitations, simply create the mice that live longest. The winning lab won by creating mice with an IGF receptor mutation. But what does the IGF pathway have to do with aging? Well, there are three interventions that consistently and reproducibly extend lifespan in a wide variety of organ...
The Advanced Pathophysiology of Insulin Resistance, Metabolic Syndrome, and Cardiovascular Disease
Переглядів 10 тис.3 роки тому
VLDL - pancreas fat Hypertrophic adipose tissue - lpl modification - higher residence time Hypertrophic adipose tissue - Lipolysis - liver beta oxidation - Gluconeogensis - susceptible to pancreas damage - T2D Subcutaneous hypertrophy - macrophage release Lipolysis THF-alpha & IL-6 - Lipolysis - DAG in liver - PKC epsilon in liver (PKC theta in muscle)
Ka Association Constant vs Kd Dissociation Constant Biochemistry made simple!
Переглядів 18 тис.3 роки тому
Ka Association Constant vs Kd Dissociation Constant Biochemistry made simple!
Beta Oxidation and Fatty Acid Metabolism (EVERYTHING YOU NEED TO KNOW FOR BIOCHEMISTRY MCAT)
Переглядів 21 тис.3 роки тому
Below is a video link that goes over every single major metabolic pathway you need to know for the MCAT!! ua-cam.com/video/CCvAey4iwYM/v-deo.html Ketogensis ua-cam.com/video/oyNYa2Wj1to/v-deo.html
The Most Important Principle you need to Understand to get an A+ in Organic Chemistry!!!
Переглядів 16 тис.3 роки тому
The Most Important Principle you must Understand to get an A in Organic Chemistry ua-cam.com/video/7gIQySNjqPk/v-deo.html Carbocation vs Carboanion Stability ua-cam.com/video/jXCbXZNtuuM/v-deo.html Acid Strength vs Base Strength ua-cam.com/video/L6_m-y5Y3qM/v-deo.html Leaving Group Stability ua-cam.com/video/NiyuQ4QGiuI/v-deo.html Induction vs Resonance ua-cam.com/video/-7klbNXGQyg/v-deo.html A...
Melting Point vs Boiling Point Polarity Trends (Rules of Organic Chemistry #5)
Переглядів 14 тис.3 роки тому
The Most Important Principle you must Understand to get an A in Organic Chemistry ua-cam.com/video/7gIQySNjqPk/v-deo.html Carbocation vs Carboanion Stability ua-cam.com/video/jXCbXZNtuuM/v-deo.html Acid Strength vs Base Strength ua-cam.com/video/L6_m-y5Y3qM/v-deo.html Leaving Group Stability ua-cam.com/video/NiyuQ4QGiuI/v-deo.html Induction vs Resonance ua-cam.com/video/-7klbNXGQyg/v-deo.html A...
Induction vs Resonance (Rules of Organic Chemistry #4)
Переглядів 20 тис.3 роки тому
The Most Important Principle you must Understand to get an A in Organic Chemistry ua-cam.com/video/7gIQySNjqPk/v-deo.html Carbocation vs Carboanion Stability ua-cam.com/video/jXCbXZNtuuM/v-deo.html Acid Strength vs Base Strength ua-cam.com/video/L6_m-y5Y3qM/v-deo.html Leaving Group Stability ua-cam.com/video/NiyuQ4QGiuI/v-deo.html Induction vs Resonance ua-cam.com/video/-7klbNXGQyg/v-deo.html A...
Lipid Biochemistry (EVERYTHING YOU NEED TO KNOW MCAT) glycerol, phospholipid, sphingosine, ceramide
Переглядів 47 тис.3 роки тому
Lipid Biochemistry (EVERYTHING YOU NEED TO KNOW MCAT) glycerol, phospholipid, sphingosine, ceramide
Leaving Group Stability Trends (Rules of Organic Chemistry #3)
Переглядів 6 тис.3 роки тому
The Most Important Principle you must Understand to get an A in Organic Chemistry ua-cam.com/video/7gIQySNjqPk/v-deo.html Carbocation vs Carboanion Stability ua-cam.com/video/jXCbXZNtuuM/v-deo.html Acid Strength vs Base Strength ua-cam.com/video/L6_m-y5Y3qM/v-deo.html Leaving Group Stability ua-cam.com/video/NiyuQ4QGiuI/v-deo.html Induction vs Resonance ua-cam.com/video/-7klbNXGQyg/v-deo.html A...
Acid Strength vs Base Strength Principles (Rules of Organic Chemistry #2)
Переглядів 10 тис.4 роки тому
The Most Important Principle you must Understand to get an A in Organic Chemistry ua-cam.com/video/7gIQySNjqPk/v-deo.html Carbocation vs Carboanion Stability ua-cam.com/video/jXCbXZNtuuM/v-deo.html Acid Strength vs Base Strength ua-cam.com/video/L6_m-y5Y3qM/v-deo.html Leaving Group Stability ua-cam.com/video/NiyuQ4QGiuI/v-deo.html Induction vs Resonance ua-cam.com/video/-7klbNXGQyg/v-deo.html A...
Carbocation vs Carbanion Stability (Rules of Organic Chemistry #1)
Переглядів 12 тис.4 роки тому
The Most Important Principle you must Understand to get an A in Organic Chemistry ua-cam.com/video/7gIQySNjqPk/v-deo.html Carbocation vs Carboanion Stability ua-cam.com/video/jXCbXZNtuuM/v-deo.html Acid Strength vs Base Strength ua-cam.com/video/L6_m-y5Y3qM/v-deo.html Leaving Group Stability ua-cam.com/video/NiyuQ4QGiuI/v-deo.html Induction vs Resonance ua-cam.com/video/-7klbNXGQyg/v-deo.html A...
Snells Law and Index of Refraction Physics Made Super Simple!
Переглядів 10 тис.4 роки тому
Introduction to Law of Reflection and Refraction ua-cam.com/video/x0j3_SruD0k/v-deo.html
Law of Reflection, Angle of Reflection & Angle of Refraction Made Super Simple! Physics
Переглядів 14 тис.4 роки тому
Law of Reflection, Angle of Reflection & Angle of Refraction Made Super Simple! Physics
Fatty Acid Synthesis EVERYTHING YOU NEED TO KNOW MCAT BIOCHEMISTRY (Map of Metabolism)
Переглядів 28 тис.4 роки тому
Fatty Acid Synthesis EVERYTHING YOU NEED TO KNOW MCAT BIOCHEMISTRY (Map of Metabolism)
Advanced Examples of Electron Orbital Hybridization (sp3 sp2 & sp Made Simple!) Organic Chemistry
Переглядів 2,8 тис.4 роки тому
Advanced Examples of Electron Orbital Hybridization (sp3 sp2 & sp Made Simple!) Organic Chemistry
Introduction to Electron Orbital Hybridization (sp3 sp2 & sp Made Super Simple!) Organic Chemistry
Переглядів 10 тис.4 роки тому
Introduction to Electron Orbital Hybridization (sp3 sp2 & sp Made Super Simple!) Organic Chemistry
DNA Mutations & DNA Repair (EVERY TYPE OF DNA REPAIR YOU NEED TO KNOW FOR MCAT BIOLOGY GENETICS)
Переглядів 43 тис.4 роки тому
DNA Mutations & DNA Repair (EVERY TYPE OF DNA REPAIR YOU NEED TO KNOW FOR MCAT BIOLOGY GENETICS)
Force of Buoyancy made super simple! Common Physics scenarios (Part 2)
Переглядів 7 тис.4 роки тому
Force of Buoyancy made super simple! Common Physics scenarios (Part 2)
Force of Buoyancy made super simple! Force of Buoyancy = Weight of Displaced Fluid Physics (Part 1)
Переглядів 10 тис.4 роки тому
Force of Buoyancy made super simple! Force of Buoyancy = Weight of Displaced Fluid Physics (Part 1)
The Ideal Gas Law PV=nRT Made Super Simple EVERYTHING you need to know for MCAT Chemistry
Переглядів 10 тис.4 роки тому
The Ideal Gas Law PV=nRT Made Super Simple EVERYTHING you need to know for MCAT Chemistry
Bernoulli’s Principle Made Super Simple with neat Trick MCAT Physics
Переглядів 16 тис.4 роки тому
Bernoulli’s Principle Made Super Simple with neat Trick MCAT Physics
Pressure in Fluid System (Rho x g x h = Pressure) Gauge Pressure vs Absolute Pressure! PHYSICS MCAT
Переглядів 9 тис.4 роки тому
Pressure in Fluid System (Rho x g x h = Pressure) Gauge Pressure vs Absolute Pressure! PHYSICS MCAT
Super Simple Trick to Solve for the Limiting Reagent EVERY TIME! Chemistry MCAT
Переглядів 17 тис.4 роки тому
Super Simple Trick to Solve for the Limiting Reagent EVERY TIME! Chemistry MCAT
Daltons Law of Partial Pressures and Henry’s Law Solubility Chemistry MCAT
Переглядів 7 тис.4 роки тому
Daltons Law of Partial Pressures and Henry’s Law Solubility Chemistry MCAT
Formal Charge vs Oxidation Number Made Super Simple with Examples Chemistry MCAT
Переглядів 9 тис.4 роки тому
Formal Charge vs Oxidation Number Made Super Simple with Examples Chemistry MCAT
Periodic Table Trends Trick (Electronegativity, Atomic Radius, Ionization Energy, Electron Affinity)
Переглядів 14 тис.4 роки тому
Periodic Table Trends Trick (Electronegativity, Atomic Radius, Ionization Energy, Electron Affinity)
Electrochemistry Galvanic/Voltaic Cell Battery Made Super Simple! MCAT Chemistry
Переглядів 30 тис.4 роки тому
Electrochemistry Galvanic/Voltaic Cell Battery Made Super Simple! MCAT Chemistry

КОМЕНТАРІ

  • @DrMahmoudinshallah
    @DrMahmoudinshallah 13 хвилин тому

    Is this on the mcat ?

  • @arlenedatiles5804
    @arlenedatiles5804 Годину тому

    What will happen if the temperatures are negative/below zero?

  • @SladkaPritomnost
    @SladkaPritomnost 3 години тому

    I suspect that even fat or lipid availability can activate mTOR (together with glucose and protein)

  • @cryptodeath854
    @cryptodeath854 7 годин тому

    At the beginning I was like..here comes the plant based Longo stuff. Listened to whole video though. I’d call it fair, but if we wait to “elderly” age to consume higher protein diets, have we already lost the battle with sarcopenia and too weak, frail, and low energy have good quality of life. What good is it to live longer, if we can’t do the things we what because of physical limitations?

  • @comangball
    @comangball 21 годину тому

    As someone with limited organic chemistry knowledge, your "we FORM a bond, and we BREAK a bond" is really helping me out. Thank u so much for these awesome videos!!

  • @violinsheetmusicblog
    @violinsheetmusicblog День тому

    High or low protein, doesn’t matter. The body is smart when given the right environment. If you stop eating protein, you will start craving protein rich foods.

    • @sciencesimplified3890
      @sciencesimplified3890 19 годин тому

      I agree protein is needed in the diet, especially if it helps satiate appetite and one has the goal of maximizing muscularity. I agree with the nutrition guidelines.

  • @thesixthcourier
    @thesixthcourier День тому

    Return of the King!

  • @alfredalvarez1857
    @alfredalvarez1857 День тому

    the king is back

  • @DrMahmoudinshallah
    @DrMahmoudinshallah 2 дні тому

    thanks for the vid but a suggestion if you can put this video above capacitance formula as it confused me when i played other one first 😅

  • @xthatswhatsuppx9772
    @xthatswhatsuppx9772 2 дні тому

    Can someone help! At 1:35, he adds electrons to the OH group so that it can leave. However, I though OH- was a bad leaving group so how does that work??

    • @sciencesimplified3890
      @sciencesimplified3890 2 дні тому

      There are biological enzymes that stabilize the OH, therefore facilitating the OH to leave as a leaving group… a common example is an enzyme protonates OH so it can leave as H2O

    • @xthatswhatsuppx9772
      @xthatswhatsuppx9772 2 дні тому

      ​@@sciencesimplified3890 I apologize as I realize you answered this in a different comment!! But thank you so much for such a quick response!

  • @samantharaymonddd
    @samantharaymonddd 3 дні тому

    omg this is the best explanation ever. thank you so much!

  • @alexaldosari1545
    @alexaldosari1545 4 дні тому

    This is a better explanation than the Princeton review damn I am impressed fr

  • @amaliasanches2951
    @amaliasanches2951 5 днів тому

    thank you so much for this

  • @abrahamhamadi2804
    @abrahamhamadi2804 6 днів тому

    Amazing video!

  • @getitdone0010
    @getitdone0010 6 днів тому

    thank youuuu

  • @getitdone0010
    @getitdone0010 6 днів тому

    thank youuuuuu

  • @brittnhuli
    @brittnhuli 7 днів тому

    Awesome videos. Just wish you would crop out the “undo paint stroke” portion, i can’t stop looking at that instead of your lecture.

  • @sadprose651
    @sadprose651 7 днів тому

    guys i think it’s because the water is orderly

  • @wdre2we2eweqwe12
    @wdre2we2eweqwe12 7 днів тому

    schooch downn gang

  • @VarshaKatoju
    @VarshaKatoju 11 днів тому

    this video is absolutely amazing oh my god thank you so much

  • @gemma3960
    @gemma3960 12 днів тому

    im a visual learner and didnt even think to lay them out this way. this helped a lot before my exam, thank you!

  • @benzo4336
    @benzo4336 12 днів тому

    This made sense. Thank you

  • @TheACLP
    @TheACLP 13 днів тому

    Do I have to memorize all of it?

    • @sciencesimplified3890
      @sciencesimplified3890 13 днів тому

      No, just understand the big picture concepts…. But details about glycolysis and Krebs cycle are high yield

  • @user-ei9qe9py6h
    @user-ei9qe9py6h 13 днів тому

    I search for a topic and whenever his videos come up i get so excited knowing its going to be a painless session unlike other chanells. Best mcat tutor hands down!!!

  • @justinegomez9744
    @justinegomez9744 14 днів тому

    this was SO helpful- thank you!!!!

  • @theodoredecartierdyves1194
    @theodoredecartierdyves1194 16 днів тому

    ILY

  • @simba_DIY
    @simba_DIY 17 днів тому

    Great video I wish the quality and resolution little bit better so I can zoom in the video my eyes aren't that great .

  • @sophiamears8263
    @sophiamears8263 17 днів тому

    Your enthusiasm has me LAUGHING thank you for this energy as I am suffering in boredom studying for the MCAT😂

  • @dezhiliu1687
    @dezhiliu1687 20 днів тому

    its embarrassing how i never understood them until this video

  • @manuelread2283
    @manuelread2283 21 день тому

    Extremely high quality explanation

  • @zazzawi0099
    @zazzawi0099 21 день тому

    trick to remember equation is Q = MCAT 😅

  • @zazzawi0099
    @zazzawi0099 22 дні тому

    so in summary: FORMAL CHARGE FC = #Ve in periodic table - #Ve it has in compound (include bonds/ Ve) Oxidation # = number of tug of way it won (- for winner) (only count bonds NOT valence e) I hope I summarized it right, thank you A TON!

  • @DrMahmoudinshallah
    @DrMahmoudinshallah 22 дні тому

    Thanks man I love you

  • @Revire4
    @Revire4 22 дні тому

    This is a little too underatedddddddddd

  • @stunart
    @stunart 22 дні тому

    Great explanation

  • @avatz4524
    @avatz4524 23 дні тому

    Your explanation was excellent ❤❤

  • @DrMahmoudinshallah
    @DrMahmoudinshallah 23 дні тому

    bahbk fash5 i wanna kiss u

  • @alaamahmoud9889
    @alaamahmoud9889 27 днів тому

    Masterpiece , thank you so much ❤

  • @malenamataloni2430
    @malenamataloni2430 28 днів тому

    THANK YOUUU!!! MAKING MCAT SO MUCH EASIER :)

  • @blas8481
    @blas8481 Місяць тому

    @sciencesimplified hello! did you ever end up making a video on the Ki? Thanks!

  • @4rV
    @4rV Місяць тому

    I love you mannn ❤

  • @chriscorrea3840
    @chriscorrea3840 Місяць тому

    amaxing

  • @zazzawi0099
    @zazzawi0099 Місяць тому

    AWESOME!! Can you please make videos about lab techniques for the mcat like column chromatography?

  • @zazzawi0099
    @zazzawi0099 Місяць тому

    GOD BLESS YOU!! Best of luck for everyone taking MCAT <3

  • @annakarki5336
    @annakarki5336 Місяць тому

    Life saver!!! I was losing my mind trying to understand and absorb this concept because my Biochem classes never talked about Beta oxidation and Fatty acid metabolism. Your video was the only one that I understood completely. Thank you so much for this!!

  • @SaiBolleddula-xi8ks
    @SaiBolleddula-xi8ks Місяць тому

    Surely magnitude of the electric field at 3m will be 6x10^9, not 2x10^9?

  • @muhammadrustamkhan1687
    @muhammadrustamkhan1687 Місяць тому

    I can you have inculcated this concept in my mind .... I am simply pleased and you not just pure love but pure blessings for many like me...

  • @sandeepbhatia2040
    @sandeepbhatia2040 Місяць тому

    Exceptional !! Each and every video is par excellence. The way you have integrated the concepts of general chemistry and organic chemistry with biochemistry is marvellous. I went through all of your videos of organic chemistry and biochemistry at a stretch in a span of 2 days to have a clear understanding of biochemistry concepts which enabled me see the bigger picture and micro details of biochemistry simultaneously. You have put everything in each and every video to have a clear and firm understanding of the concepts. I find myself short of words to thank you.

  • @aeriellebelk9941
    @aeriellebelk9941 Місяць тому

    Thank you! This was very helpful!

  • @jehankamoona9378
    @jehankamoona9378 Місяць тому

    I love how you politely yell at me. works every time lol thank you very much